과립 세포형 법낭아세포종의 병리조직학적 및 전자현미경적 연구
Histopathologic and Electron Microscopic Study of Granular Cell Ameloblastoma
조재오, 박민갑,
소속 상세정보
조재오 ( ) - 조선대학교 치과대학 구강병리학교실,
박민갑 ( ) - 조선대학교 치과대학 구강병리학교실,
KMID : 0829219990230020179
Abstract
The purpose of this study was to evaluate granular cell ameloblastoma, for this study 20 cases of ameloblastoma were used and histopathologic, immunohistochemical (p53 protein, proliferating cell nuclear antigen) , and electron microscopic examinatims were performed.
Attained result as follows.
1. Average age of granular cell ameloblastoma patients were 25 yr 6 month.
2. Granular cells were occurred at the center of the follicular type ameloblastoma as a result of sguamous metaplasia. But other case. it was arised in the plexiform type ameloblastoma and tumor cells were replased by granular cells.
3. The reaction of proliferatin cell nuclear antigen was revealed intensive reaction at the periphery of follicular ameloblastoma, but negative to minimal reaction was noted on granular cells.
4. In case of p53 protein, minimal positive reaction was noted on the tumor cells. But in granular cells, minunal positive to negative reaction was appeard.
5. In electron microscopic examination, electron dense materials were noted in side of the granules. And the shape of granules were various and encapsnlated by single membrane
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